Sir John de Sutton V (c. 1380 – 29 August 1406) was born at Dudley Castle, Staffordshire, or at Coleshill, Warwickshire, the son of Sir John de Sutton IV (6 December 1361 – 10 March 1395), Master of Dudley Castle and Alice Despencer, of Carlington (died 1392). John de Sutton IV was the son of Sir John de Sutton III (1339 – c. 1370 or 1376), Knight, Master of Dudley Castle, and wife (m. 25 December 1357) Katherine de Stafford (Staffordshire, 1340 or 1348 – December 1361). Katherine was the daughter of Ralph de Stafford, 1st Earl of Stafford and Margaret de Audley, 2nd Baroness Audley.
John de Sutton married Constance Blount (died September 1432), the daughter of Sir Walter Blount, of Barton, Derbyshire, who died at the Battle of Shrewsbury on 21 July 1403, and his wife Sancha de Ayala (died 1418), the daughter of Diego Gómez, Alcalde of Toledo and Inés Alfonso de Ayala. John de Sutton V's son was John Sutton, 1st Baron Dudley.